Microdialysis study of imipenem distribution in the peritoneal fluid of rats with experimental acute pancreatitis.

نویسندگان

  • Sandrine Lefeuvre
  • Sandrine Marchand
  • Claudine Pariat
  • Isabelle Lamarche
  • William Couet
چکیده

Imipenem distribution was characterized by microdialysis in the peritoneal fluid of rats with experimental pancreatitis. The ratios of peritoneal fluid to blood area under unbound concentration-versus-time curves were close to unity, suggesting that imipenem was not degraded in peritoneal fluid.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 52 4  شماره 

صفحات  -

تاریخ انتشار 2008